Thursday, July 15, 2010
Regulatory RNA
Number of RNA can downregulate gene expression is a complementary part of the DNA or mRNA of the gene. MicroRNAs (miRNAs, nt 1921-1922) found in eukaryotes and act through RNA interference (RNAi), where the effector complex of miRNA and enzymes can break down mRNA that is complementary miRNA inhibits the RNA from a curve, or accelerate its degradation. [29] [30] Although the small interfering RNAs (siRNAs, 20-25 nt) often leads to breakdown of RNA is also its own sources of siRNA. [31] [32] Law siRNAs through RNAi fashion similar to miRNAs. Some of the miRNA and siRNA can cause target genes is methylated, decreasing or increasing the transcription of these genes. [33] [34] [35] The animals are RNAS Piwi interacting (Pirna, 29-30 nt) involved in germ line cells and presumably protects transposons, and an important role in gametogenesis
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